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Travel and accomodation support for one representative of FEMAMA's affiliate to

attend Brazilian Forum of Breast Cancer Patient Organizations, São Paulo 2016

Brazil

Fundação Laço Rosa - Associação Laço Rosa pela

cura do câncer de mama www.fundacaolacorosa.com Non-financial contributions to Patient Organisations (in-kind) kBRL 1.35

Travel and accomodation support for one representative to attend All Together

Against Cancer Congress, São Paulo 2016

Brazil

Fundação Laço Rosa - Associação Laço Rosa pela

cura do câncer de mama www.fundacaolacorosa.com Non-financial contributions to Patient Organisations (in-kind)

kBRL 2.15

Participation in Roche's Long-Term Capacity Building in Management and Project

Elaboration - Phase 1 - for two patient group representatives - São Paulo, 2015

Brazil

Fundação Laço Rosa - Associação Laço Rosa pela

cura do câncer de mama www.fundacaolacorosa.com Non-financial contributions to Patient Organisations (in-kind) kBRL 3.00

Travel and accomodation support for one representative to to Latin American

Forum on Biossimilars, Brasilia, 2016

Brazil

Fundação Laço Rosa - Associação Laço Rosa pela

cura do câncer de mama www.fundacaolacorosa.com Non-financial contributions to Patient Organisations (in-kind) kBRL 3.48

Travel and accomodation support for one representative to attend Oncoguia's

Public Policy Forum in Brasilia

Brazil

Fundação Laço Rosa - Associação Laço Rosa pela

cura do câncer de mama www.fundacaolacorosa.com Non-financial contributions to Patient Organisations (in-kind) kBRL 4.12

Support for the participation of two representatives at the Roche Cervical Cancer

Workshop in São Paulo, 2015

Brazil

Fundação Laço Rosa - Associação Laço Rosa pela

cura do câncer de mama www.fundacaolacorosa.com Non-financial contributions to Patient Organisations (in-kind) kBRL 7.00

Attendance at Capacity Building in Project Elaboration to Roche's Call for Proposals

Brazil

Fundação Laço Rosa - Associação Laço Rosa pela

cura do câncer de mama www.fundacaolacorosa.com Non-financial contributions to Patient Organisations (in-kind) kBRL 8.23

Logistic support for one representative to attend the IEEPO – International

Experience Exchange for Patient Organisations, Copenhagen, 2016

Brazil

Fundação Laço Rosa - Associação Laço Rosa pela

cura do câncer de mama www.fundacaolacorosa.com Non-financial contributions to Patient Organisations (in-kind) kBRL 9.25

Travel and accomodation support for one representative to attend World Cancer

Congress in Paris

Brazil

Fundação Laço Rosa - Associação Laço Rosa pela

cura do câncer de mama www.fundacaolacorosa.com Non-financial contributions to Patient Organisations (in-kind) kBRL 10.38

Logistic Support to Roche Metastatic Breast Cancer Meeting in Milan

Brazil

Fundação Laço Rosa - Associação Laço Rosa pela

cura do câncer de mama www.fundacaolacorosa.com Non-financial contributions to Patient Organisations (in-kind) kBRL 11.90

Participation in Roche's Long-Term Capacity Building in Management - Phase 2 -

September to November/2016 at patient group's office.

Brazil

Fundação Laço Rosa - Associação Laço Rosa pela

cura do câncer de mama www.fundacaolacorosa.com Financial contributions to Patient Organisations kBRL 19.50

Capacity building for Fundação Laço Rosa volunteers.

Brazil

Fundação Laço Rosa - Associação Laço Rosa pela

cura do câncer de mama www.fundacaolacorosa.com Financial contributions to Patient Organisations kBRL 127.46

Sponsorship of survey focusing on Rio de Janeiro patient journey and a forum held

on May presenting the results.

Brazil GADA - Grupo de Amparo ao Paciente com AIDS www.gada.org.br Non-financial contributions to Patient Organisations (in-kind) kBRL 7.00

Attendance at Capacity Building in Project Elaboration to Roche's Call for Proposals

Brazil GADA - Grupo de Amparo ao Paciente com AIDS www.gada.org.br Non-financial contributions to Patient Organisations (in-kind) kBRL 8.14

Support for the participation of two representatives at the Roche Colorectal Cancer

Workshop in São Paulo, 2016

Brazil GADA - Grupo de Amparo ao Paciente com AIDS www.gada.org.br Financial contributions to Patient Organisations kBRL 26.49

Prevention and early diagnosis program of breast and cervical cancer for a group

of women in São José do Rio Preto

Brazil

GAPO - Associação do Grupo de Apoio ao Paciente

Onco-Hematologico do Estado do Ceará www.gapo.com.br Non-financial contributions to Patient Organisations (in-kind)

kBRL 2.15

Participation in Roche's Long-Term Capacity Building in Management and Project

Elaboration - Phase 1 - for two patient group representatives - São Paulo, 2015

Brazil

GAPO - Associação do Grupo de Apoio ao Paciente

Onco-Hematologico do Estado do Ceará www.gapo.com.br Non-financial contributions to Patient Organisations (in-kind) kBRL 3.48

Travel and accomodation support for one representative to attend Oncoguia's

Public Policy Forum in Brasilia

Brazil

GAPO - Associação do Grupo de Apoio ao Paciente

Onco-Hematologico do Estado do Ceará www.gapo.com.br Non-financial contributions to Patient Organisations (in-kind) kBRL 7.00

Attendance at Capacity Building in Project Elaboration to Roche's Call for Proposals

Brazil

GAPO - Associação do Grupo de Apoio ao Paciente

Onco-Hematologico do Estado do Ceará www.gapo.com.br Non-financial contributions to Patient Organisations (in-kind) kBRL 11.90

Participation in Roche's Long-Term Capacity Building in Management - Phase 2 -

September to November/2016 at patient group's office.

Brazil

Gruparj Petrópolis - Grupo de Pacientes Artríticos do

Rio de Janeiro em Petrópolis www.gruparjpetropolis.com.br Non-financial contributions to Patient Organisations (in-kind) kBRL 3.46

Travel and accomodation support for one representative to to Latin American

Forum on Biossimilars, Brasilia, 2016

Brazil

Gruparj Petrópolis - Grupo de Pacientes Artríticos do

Rio de Janeiro em Petrópolis www.gruparjpetropolis.com.br Non-financial contributions to Patient Organisations (in-kind) kBRL 7.00

Attendance at Capacity Building in Project Elaboration to Roche's Call for Proposals

Brazil

Gruparj Petrópolis - Grupo de Pacientes Artríticos do

Rio de Janeiro em Petrópolis www.gruparjpetropolis.com.br Non-financial contributions to Patient Organisations (in-kind) kBRL 12.85

Participation in Roche's Capacity Building for Cystic Fibrosis and Rheumatoid

Arthritis in Management and HTA, Sao Paulo, June 2016.

Brazil

GRUPAR - RP - Grupo de Apoio ao Paciente

Reumático de Ribeirão Preto www.grupar-rp.org.br Non-financial contributions to Patient Organisations (in-kind) kBRL 7.00

Attendance at Capacity Building in Project Elaboration to Roche's Call for Proposals

Brazil Grupo Rosa e Amor www.gruporosaeamor.org.br Non-financial contributions to Patient Organisations (in-kind) BRL 1'050.00

Travel and accomodation support for one representative of FEMAMA's affiliate to

attend Brazilian Forum of Breast Cancer Patient Organizations, São Paulo 2016

Brazil

Grupo Rosa e Amor

www.gruporosaeamor.org.br Non-financial contributions to Patient Organisations (in-kind)

kBRL 2.15

Participation in Roche's Long-Term Capacity Building in Management and Project

Elaboration - Phase 1 - for two patient group representatives - São Paulo, 2015

Brazil Grupo Rosa e Amor www.gruporosaeamor.org.br Non-financial contributions to Patient Organisations (in-kind) kBRL 4.12

Support for the participation of two representatives at the Roche Cervical Cancer

Workshop in São Paulo, 2015

Brazil Grupo Rosa e Amor www.gruporosaeamor.org.br Non-financial contributions to Patient Organisations (in-kind) kBRL 7.00

Attendance at Capacity Building in Project Elaboration to Roche's Call for Proposals

Brazil

Grupo Rosa e Amor

www.gruporosaeamor.org.br Non-financial contributions to Patient Organisations (in-kind)

kBRL 11.90

Participation in Roche's Long-Term Capacity Building in Management and Project

Elaboration - Phase 1 - for two patient group representatives - São Paulo, 2015

Brazil Grupo Rosa e Amor www.gruporosaeamor.org.br Financial contributions to Patient Organisations kBRL 21.24

Awareness Campaign - Prevention and early diagnosis program for cervical cancer

in Valinhos

Brazil

GRUPO OTIMISMO - Grupo Otimismo de Apoio ao

Portador de Hepatite www.hepato.com Financial contributions to Patient Organisations kBRL 80.00

Improving patient voice using social media: best practice sharing with other

pathologies

Brazil

HUMSOL - Instituto Humanista de Desenvolvimento

Social www.humsol.com.br Non-financial contributions to Patient Organisations (in-kind) BRL 1'050.00

Travel and accomodation support for one representative of FEMAMA's affiliate to

attend Brazilian Forum of Breast Cancer Patient Organizations, São Paulo 2016

Brazil

HUMSOL - Instituto Humanista de Desenvolvimento

Social www.humsol.com.br Non-financial contributions to Patient Organisations (in-kind) kBRL 1.35

Travel and accomodation support for one representative to attend All Together

Against Cancer Congress, São Paulo 2016

Brazil

HUMSOL - Instituto Humanista de Desenvolvimento

Social www.humsol.com.br Non-financial contributions to Patient Organisations (in-kind)

kBRL 2.15

Participation in Roche's Long-Term Capacity Building in Management and Project

Elaboration - Phase 1 - for two patient group representatives - São Paulo, 2015

Brazil

HUMSOL - Instituto Humanista de Desenvolvimento

Social www.humsol.com.br Non-financial contributions to Patient Organisations (in-kind) kBRL 4.12

Support for the participation of two representatives at the Roche Cervical Cancer

Workshop in São Paulo, 2015

Brazil

HUMSOL - Instituto Humanista de Desenvolvimento

Social www.humsol.com.br Non-financial contributions to Patient Organisations (in-kind) kBRL 8.14

Support for the participation of two representatives at the Roche Colorectal Cancer

Workshop in São Paulo, 2016

Brazil

HUMSOL - Instituto Humanista de Desenvolvimento

Social www.humsol.com.br Non-financial contributions to Patient Organisations (in-kind) kBRL 9.25

Travel and accomodation support for one representative to attend World Cancer

Congress in Paris

Brazil

HUMSOL - Instituto Humanista de Desenvolvimento

Social www.humsol.com.br Non-financial contributions to Patient Organisations (in-kind) kBRL 11.90

Participation in Roche's Long-Term Capacity Building in Management - Phase 2 -

September to November/2016 at patient group's office.

Brazil

HUMSOL - Instituto Humanista de Desenvolvimento

Social www.humsol.com.br Financial contributions to Patient Organisations kBRL 6.28

Volunteer capacity building

Brazil IMAMA - Instituto da Mama do Rio Grande do sul www.imama.org.br Non-financial contributions to Patient Organisations (in-kind) BRL 730.00

Support for the participation of one representative at the Latin American Patient

Organisations Workshop (LAPOW) in Lima, 2016

Brazil IMAMA - Instituto da Mama do Rio Grande do sul www.imama.org.br Non-financial contributions to Patient Organisations (in-kind) kBRL 11.90

Participation in Roche's Long-Term Capacity Building in Management - Phase 2 -

September to November/2016 at patient group's office.

Brazil IMAMA - Instituto da Mama do Rio Grande do sul www.imama.org.br Financial contributions to Patient Organisations kBRL 100.00

Mapping and identifying the main issues and stakeholders involved in cancer and

holding a meeting for patients and stakeholders in June, Porto Alegre.

Brazil Instituto Roda da Vida www.institutorodadavida.org.br Non-financial contributions to Patient Organisations (in-kind) BRL 730.00

Support for the participation of one representative at the Latin American Patient

Organisations Workshop (LAPOW) in Lima, 2016

Brazil

Instituto Roda da Vida

www.institutorodadavida.org.br Non-financial contributions to Patient Organisations (in-kind)

kBRL 2.15

Participation in Roche's Long-Term Capacity Building in Management and Project

Elaboration - Phase 1 - for two patient group representatives - São Paulo, 2015

Brazil Instituto Roda da Vida www.institutorodadavida.org.br Non-financial contributions to Patient Organisations (in-kind) kBRL 7.00

Attendance at Capacity Building in Project Elaboration to Roche's Call for Proposals

Brazil Instituto Roda da Vida www.institutorodadavida.org.br Non-financial contributions to Patient Organisations (in-kind) kBRL 8.14

Support for the participation of two representatives at the Roche Colorectal Cancer

Workshop in São Paulo, 2016

Brazil Instituto Roda da Vida www.institutorodadavida.org.br Non-financial contributions to Patient Organisations (in-kind) kBRL 11.90

Participation in Roche's Long-Term Capacity Building in Management - Phase 2 -

September to November/2016 at patient group's office.

Brazil

Instituto Roda da Vida

www.institutorodadavida.org.br Financial contributions to Patient Organisations

kBRL 113.84